| | |
Protocol-A
|
Protocol-B
|
Protocol-C
|
Protocol-D
|
|---|
|
Background*
|
|
Hepatitis B
| |
5 (3.5)
|
8 (6.8)
|
6 (6.9)
|
6 (9.0)
|
|
Hepatitis C
| |
36 (25.0)
|
35 (29.9)
|
17 (19.5)
|
19 (28.4)
|
|
LC
| |
104 (72.2)
|
75 (64.1)
|
65 (74.7)
|
42 (62.7)
|
|
LC-B
| |
9 (6.3)
|
8 (6.8)
|
3 (3.4)
|
2 (3.0)
|
|
LC-C
| |
75 (52.1)
|
51 (43.6)
|
45 (51.7)
|
28 (41.8)
|
|
LC-Alcoholic
| |
13 (9.0)
|
9 (7.7)
|
11 (12.6)
|
13 (19.4)
|
|
NASH
| |
5 (3.5)
|
1 (0.9)
|
0.(0.0)
|
0 (0.0)
|
|
Others
| |
5 (3.5)
|
9 (7.7)
|
8 (9.2)
|
2 (3.0)
|
|
Fatty liver
| |
1 (0.7)
|
0 (0.0)
|
3 (3.4)
|
2 (3.0)
|
|
Others
| |
2 (1.4)
|
2 (1.7)
|
0 (0.0)
|
0 (0.0)
|
|
Characteristics
|
|
Size of tumor** (mm)
| |
17.08 ± 6.42
|
16.85 ± 5.88
|
16.70 ± 6.27
|
16.60 ± 6.29
|
|
Range
| |
3.0-30.0
|
5.6-30.0
|
7.0-30.0
|
6.6 − 29.0
|
| |
<20 mm
|
89 (61.8)
|
73 (62.4)
|
62 (71.3)
|
45 (67.2)
|
| |
>20 mm
|
55 (38.2)
|
44 (37.6)
|
25 (28.7)
|
22 (32.8)
|
|
Number of tumors
|
1-3
|
109 (75.7)
|
97 (82.9)
|
65 (74.7)
|
47 (70.1)
|
| |
4-6
|
14 (9.7)
|
8 (6.8)
|
7 (8.0)
|
6 (9.0)
|
| |
7-9
|
6 (4.2)
|
3 (2.6)
|
1 (1.1)
|
4 (6.0)
|
| |
>10
|
15 (10.4)
|
9 (7.7)
|
14 (16.1)
|
10 (14.9)
|
|
Diagnosis methods*
|
|
Biopsy
| |
5 (3.5)
|
1 (0.9)
|
0 (0.0)
|
0 (0.0)
|
|
CE-MRI
| |
33 (22.9)
|
39 (33.3)
|
31 (35.6)
|
14 (20.9)
|
|
CTAP/CTHA
| |
10 (6.9)
|
9 (7.7)
|
10 (11.5)
|
9 (13.4)
|
|
Angiography
| |
29 (20.1)
|
43 (36.8)
|
10 (11.5)
|
26 (38.8)
|
|
Lipiodol CT
| |
12 (8.3)
|
15 (12.8)
|
4 (4.6)
|
3 (4.5)
|
|
Sonography
| |
42 (29.1)
|
56 (47.9)
|
40 (46.0)
|
28 (41.8)
|
|
Growth of tumor
| |
45 (31.3)
|
27 (23.1)
|
37 (42.5)
|
11 (16.4)
|
|
Increased tumor markers
| |
78 (54.2)
|
70 (59.8)
|
45 (51.7)
|
34 (50.7)
|
- Note; Data presented as number (%) of patients or mean ± standard deviation (SD);
- LC, Liver cirrhosis; NASH, non-alcoholic steatohepatitis, CE-MRI, Contrast-enhanced magnetic resonance imaging;
- CTAP, computed tomography during arterial portography; CTHA, computed tomography during hepatic arteriography
- ** Background and diagnosis methods were made by multiple selections.
- * Tumor selected as target tumor for quantitaive analysis.
