Skip to main content

Advertisement

Table 3 Cox proportional hazard stratified based on a) ER-status, and b) menopausal status relating BC patients with coexisting AD-HS to BC patients without

From: Autoimmune diseases and hypersensitivities improve the prognosis in ER-negative breast cancer

a) Number of patients included in the analysis N=332 and N=695, respectively
  Patients with ER-negative tumors Patients with ER-positive tumors
  HR 95% CI for HR p-value HR 95% CI for HR p-value
   Lower Upper    Lower Upper  
AD-HS 0.53 0.30 0.96 0.036 0.98 0.70 1.37 0.909
T1 1.00 Ref Ref   1.00 Ref Ref  
T2 1.30 0.95 1.77 0.097 1.60 1.26 2.03 <0.001
T3 2.62 1.69 4.08 <0.001 1.97 1.33 2.91 0.001
T4 3.86 0.91 16.42 0.067 - - - -
N0 1.00 Ref Ref   1.00 Ref Ref  
N1 1.63 1.17 2.27 0.004 1.28 1.00 1.64 0.054
N2 2.29 1.51 3.49 <0.001 1.38 0.98 1.93 0.064
N3 2.72 1.54 4.81 0.001 2.61 1.68 4.06 <0.001
Screening 0.59 0.27 1.26 0.174 0.75 0.51 1.11 0.149
b) Number of patients included in the analysis N=499 and N=959, respectively
  Premenopausal BC patients Postmenopausal BC patients
  HR 95% CI for HR p-value HR 95% CI for HR p-value
   Lower Upper    Lower Upper  
AD-HS 0.63 0.38 1.04 0.073 1.02 0.77 1.34 0.898
T1 1.00 Ref Ref   1.00 Ref Ref  
T2 1.22 0.91 1.65 0.190 1.48 1.23 1.78 <0.001
T3 3.29 2.16 5.01 <0.001 1.73 1.25 2.39 0.001
T4 - - - - 1.68 0.53 5.31 0.377
N0 1.00 Ref Ref   1.00 Ref Ref  
N1 1.54 1.11 2.13 0.009 1.58 1.28 1.95 <0.001
N2 2.72 1.85 4.00 <0.001 1.84 1.43 2.39 <0.001
N3 3.63 2.07 6.36 <0.001 2.95 2.15 4.05 <0.001
Screening 0.66 0.29 1.50 0.319 0.76 0.59 0.97 0.030
  1. Both models are adjusted for age at BC diagnosis, T- and N-status of the tumor, and screening simultaneously.
  2. T1 and N0 were reference values for respective category.