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Table 2 Plasma concentrations (μg/ml) of vancomycin or BT2-peg2-vancomycin (BTV) in the osteomyelitis animals following 21 days of treatment

From: Treatment of Methicillin-resistant Staphylococcus aureus experimental Osteomyelitis with bone-targeted Vancomycin

  n Plasma concentration (μg/ml) Time (h) after last dose
   Median Range
Vancomycin HCl twice daily 16 0.71 0.24-2.00 12
BTV twice daily 13 129.98 74.56-207.90 12
BTV twice daily for 3.5 days and then every four days 14 0.88 0.00-4.14 48
BTV once per week 15 0.00 0.00-0.34 168