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Table 1 Kidney weights, creatinine, BUN and albumin (range) values after treatment with vancomycin HCl or BT2-peg2-vancomycin diformate (BTV)

From: Treatment of Methicillin-resistant Staphylococcus aureus experimental Osteomyelitis with bone-targeted Vancomycin

Group Kidney weight (grams) Creatinine (mg/dl) BUN (mg/dl) Albumin (g/dl)
No treatment 1.4 (1.2-1.9) 0.5 (0.5-0.6) 20 (17–25) 3.6 (3.3-3.9)
Vancomycin HCl twice daily 1.4 (1.1-1.7) 0.5 (0.4-0.6) 18.5 (15–21) 3.4 (3.1-3.6)
BTV twice daily 4.1 (2.4-6.0) 1.5 (1.2-2.2) 76.5 (56–114) 2.8 (2.6-3.0)
BTV twice daily for 3.5 days and then every four days 1.7 (1.3-2.2) 0.6 (0.5-1.2) 31 (22–47) 3.6 (3.1-4)
BTV once per week 1.5 (1.4-1.8) 0.5 (0.4-0.6) 19 (17–21) 3.6 (3.3-3.8)