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Table 2 Biological activity of FVIII secreted by Hek-293/BMN-FVIIIΔB-I-GFP
| Sample | % of GFP expression | Activity (%) | IU/mL |
|---|---|---|---|
| Culture medium DMEN | - | 1.5 | - |
| S. Cell pop. 01 | 74.0 | 14.0 | 0.1 |
| S. Cell pop. 02 | 80.0 | 11.1 | 0.1 |
| S. Cell pop. 03 | 76.5 | 10.0 | 0.1 |
| S. Cell pop. 04 | 72.1 | 34.6 | 0.3 |
| S. Cell pop. 05 | 70.0 | 41.9 | 0.4 |
| S. Cell pop. 06 | 70.5 | 21.7 | 0.2 |
| S. Cell pop. 07 | 68.1 | 1.9 | 0.0 |
| S. Cell pop. 08 | 63.8 | 2.2 | 0.0 |
| S. Cell pop. 09 | 44.3 | 2.9 | 0.0 |
| S. Cell pop. 10 | 43.4 | 20.1 | 0.2 |
| S. Cell pop. 11 | 44.9 | 4.1 | 0.0 |
| S. Cell pop. 12 | 48.2 | 75.8 | 0.7 |
| S. Cell pop. 13 | 53.6 | 18.5 | 0.1 |
| S. Cell pop. 14 | 62.5 | 47.9 | 0.4 |
| S. Cell pop. 15 | 48.6 | 37.1 | 0.3 |
