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Table 1 Averaged kink and tilt angles in degree of the individual TMDs and the TMDs of the monomer

From: Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs

  Kink [°] Tilt [°]
Individual TMDs   
TMD110-32 156.2 ± 9.4 14.1 ± 5.5
TMD236-58 142.6 ± 7.3 8.9 ± 4.2
TMD11-32 147.5 ± 9.1 20.1 ± 4.2
TMD2-F44Y 136.1 ± 21.0 20.8 ± 4.9
TMD2-Y42/45S 162.0 ± 8.1 8.5 ± 3.5
TMD2-Y42/45F 153.0 ± 11.3 7.8 ± 3.9
Monomer   
M NL   
TMD1 161.7 ± 5.6 24.4 ± 6.9
TMD2 143.1 ± 8.4 28.8 ± 11.8
M L   
TMD1 159.2 ± 4.3 12.8 ± 4.3
TMD2 159.6 ± 5.7 18.6 ± 2.9
  1. The values represent averages taken over the entire length of each of the simulations.