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Table 1 Demographics and laboratory values between the study groups

From: Effect of 6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride (Voluven®) on complications after subarachnoid hemorrhage: a retrospective analysis

  Non-HES group (n=72) HES group (n=57) p value
Demographic characteristics    
Age (years) 57 (48–63) 57 (46–65) 0.58
Weight (kilogram) 75 (62.5-87) 79 (63.5-97.5) 0.18
Male 24 (33.3%) 18 (31.6%) 0.83
Female 48 (66.4%) 39 (68.4%)
Caucasian 38 (52.8%) 32 (56.1%) 0.88
African-American 27 (37.5%) 19 (33.3%)
Others 7 (9.7%) 6 (10.5%)
Pre-existing medical conditions at admission    
No past medical history 7 (9.7%) 3 (5.3%) 0.34
Ischemic heart disease 4 (5.6%) 10 (17.5%) 0.03
Congestive heart failure 4 (5.6%) 4 (7%) 0.73
Cerebro-vascular accident- stroke 2 (2.8%) 2 (3.5%) 0.81
Cerebro-vascular accident- transient ischemic attack 0 (0%) 2 (3.5%) 0.11
Previous history of Subarachnoid Hemorrhage 0 (0%) 0 (0%) NA
Epilepsy 1 (1.4%) 1 (1.8%) 0.86
Hypertension 40 (55.6%) 43 (75.4%) 0.02
Chronic renal failure- no dialysis 2 (2.8%) 3 (5.3%) 0.46
Chronic renal failure- Peritoneal or Hemodialysis 0 (0%) 0 (0%) NA
Diabetes- not on insulin 2 (2.8%) 3 (5.3%) 0.47
Diabetes- treated with insulin 3 (4.2%) 5 (8.8%) 0.28
COPD ( no home oxygen) 3 (4.2%) 4 (7%) 0.48
COPD (home oxygen) 0 (0%) 0 (0%) NA
Smoker 22 (30.6%) 11 (19.3%) 0.14
Family history of Subarachnoid Hemorrhage 6 (8.3%) 2 (3.5%) 0.26
Home medication at admission    
Patient not on any home medications 18 (25%) 10 (17.5%) 0.31
Aspirin 17 (23.6%) 20 (35%) 0.15
Clopidogrel 0 (0%) 2 (3.5%) 0.11
Statin 22 (30.6%) 12 (21%) 0.22
Subarachnoid Hemorrhage grading at admission    
Hunt-Hess grade    
Hunt-Hess grade 1 6 (8.3%) 4 (7%)  
Hunt-Hess grade 2 36 (50%) 32 (56.1%)
Hunt-Hess grade 3 17 (23.6%) 13 (22.8%)
Hunt-Hess grade 4 6 (8.3%) 2 (3.5%)
Hunt-Hess grade 5 7 (9.7%) 6 (10.5%) 0.82
Fisher grade    
Fisher grade 1 4 (5.5%) 1 (1.8%) 0.04
Fisher grade 2 12 (16.7%) 2 (3.5%)
Fisher grade 3 45 (62.5%) 47 (82.4%)
Fisher grade 4 11 (15.3%) 7 (12.3%)
Treatment of aneurysm during this hospital stay    
Open Craniotomy and aneurysm clipping 31 (43%) 32 (56.1%) 0.14
Endovascular coil embolization 35 (48.6%) 22 (38.5%) 0.25
Laboratory investigation during hospital stay    
Hemoglobin at admission (g.dl-1) 13 (11.6-14) 12.7 (11.5-14.3) 0.84
Lowest Hemoglobin during hospital stay (g.dl-1) 9.5 (8.3-10.7) 8.3 (7.6-9.4) 0.001
Platelet count at admission (× 109/L) 243 (206–283) 235 (194–272) 0.59
Prothrombin Time at admission (sec) 11.9 (11.1-12.8) 12.2 (11.6-13) 0.16
Partial Thromboplastin Time at admission (sec) 26.8 (24–28.8) 25.7 (23.5-27.6) 0.26
Serum Creatinine at admission (mg.dl-1) 0.8(0.6-1) 0.8(0.7-0.9) 0.46
Highest Serum Creatinine during hospital stay (mg.dl-1) 0.9 (0.8-1.2) 0.9 (0.75-1.1) 0.70
  1. Median (Interquartile Range) was reported for continuous variables and count (%) for categorical variables. Mann–Whitney U test was used to compare continuous variables and chi-square test for categorical variables.
  2. COPD Chronic obstructive pulmonary disease.
  3. ARB/ACEI Angiotensin receptor blocker/Angiotensin converting enzyme inhibitor.
  4. NA Not applicable.