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Table 1 Demographics and laboratory values between the study groups

From: Effect of 6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride (Voluven®) on complications after subarachnoid hemorrhage: a retrospective analysis

 

Non-HES group (n=72)

HES group (n=57)

p value

Demographic characteristics

   

Age (years)

57 (48–63)

57 (46–65)

0.58

Weight (kilogram)

75 (62.5-87)

79 (63.5-97.5)

0.18

Male

24 (33.3%)

18 (31.6%)

0.83

Female

48 (66.4%)

39 (68.4%)

Caucasian

38 (52.8%)

32 (56.1%)

0.88

African-American

27 (37.5%)

19 (33.3%)

Others

7 (9.7%)

6 (10.5%)

Pre-existing medical conditions at admission

   

No past medical history

7 (9.7%)

3 (5.3%)

0.34

Ischemic heart disease

4 (5.6%)

10 (17.5%)

0.03

Congestive heart failure

4 (5.6%)

4 (7%)

0.73

Cerebro-vascular accident- stroke

2 (2.8%)

2 (3.5%)

0.81

Cerebro-vascular accident- transient ischemic attack

0 (0%)

2 (3.5%)

0.11

Previous history of Subarachnoid Hemorrhage

0 (0%)

0 (0%)

NA

Epilepsy

1 (1.4%)

1 (1.8%)

0.86

Hypertension

40 (55.6%)

43 (75.4%)

0.02

Chronic renal failure- no dialysis

2 (2.8%)

3 (5.3%)

0.46

Chronic renal failure- Peritoneal or Hemodialysis

0 (0%)

0 (0%)

NA

Diabetes- not on insulin

2 (2.8%)

3 (5.3%)

0.47

Diabetes- treated with insulin

3 (4.2%)

5 (8.8%)

0.28

COPD ( no home oxygen)

3 (4.2%)

4 (7%)

0.48

COPD (home oxygen)

0 (0%)

0 (0%)

NA

Smoker

22 (30.6%)

11 (19.3%)

0.14

Family history of Subarachnoid Hemorrhage

6 (8.3%)

2 (3.5%)

0.26

Home medication at admission

   

Patient not on any home medications

18 (25%)

10 (17.5%)

0.31

Aspirin

17 (23.6%)

20 (35%)

0.15

Clopidogrel

0 (0%)

2 (3.5%)

0.11

Statin

22 (30.6%)

12 (21%)

0.22

Subarachnoid Hemorrhage grading at admission

   

Hunt-Hess grade

   

Hunt-Hess grade 1

6 (8.3%)

4 (7%)

 

Hunt-Hess grade 2

36 (50%)

32 (56.1%)

Hunt-Hess grade 3

17 (23.6%)

13 (22.8%)

Hunt-Hess grade 4

6 (8.3%)

2 (3.5%)

Hunt-Hess grade 5

7 (9.7%)

6 (10.5%)

0.82

Fisher grade

   

Fisher grade 1

4 (5.5%)

1 (1.8%)

0.04

Fisher grade 2

12 (16.7%)

2 (3.5%)

Fisher grade 3

45 (62.5%)

47 (82.4%)

Fisher grade 4

11 (15.3%)

7 (12.3%)

Treatment of aneurysm during this hospital stay

   

Open Craniotomy and aneurysm clipping

31 (43%)

32 (56.1%)

0.14

Endovascular coil embolization

35 (48.6%)

22 (38.5%)

0.25

Laboratory investigation during hospital stay

   

Hemoglobin at admission (g.dl-1)

13 (11.6-14)

12.7 (11.5-14.3)

0.84

Lowest Hemoglobin during hospital stay (g.dl-1)

9.5 (8.3-10.7)

8.3 (7.6-9.4)

0.001

Platelet count at admission (× 109/L)

243 (206–283)

235 (194–272)

0.59

Prothrombin Time at admission (sec)

11.9 (11.1-12.8)

12.2 (11.6-13)

0.16

Partial Thromboplastin Time at admission (sec)

26.8 (24–28.8)

25.7 (23.5-27.6)

0.26

Serum Creatinine at admission (mg.dl-1)

0.8(0.6-1)

0.8(0.7-0.9)

0.46

Highest Serum Creatinine during hospital stay (mg.dl-1)

0.9 (0.8-1.2)

0.9 (0.75-1.1)

0.70

  1. Median (Interquartile Range) was reported for continuous variables and count (%) for categorical variables. Mann–Whitney U test was used to compare continuous variables and chi-square test for categorical variables.
  2. COPD Chronic obstructive pulmonary disease.
  3. ARB/ACEI Angiotensin receptor blocker/Angiotensin converting enzyme inhibitor.
  4. NA Not applicable.