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Table 5 Study population characteristics of IBC cases by menopausal status (age <50 yr vs. >=50 yr)

From: Characterizing inflammatory breast cancer among Arab Americans in the California, Detroit and New Jersey Surveillance, Epidemiology and End Results (SEER) registries (1988–2008)

 

All IBC

Premenopausal IBC

Postmenopausal IBC

p-value

(n=9,135)

(n=2811)

(n=6,324)

n

(%)

n

(%)

n

(%)

Race

 

Non-Hispanic White

6,035

(66.1%)

1,565

(25.9%)

4,470

(74.1%)

<0.0001

 

Non-Hispanic Black

1,085

(11.9%)

389

(35.9%)

696

(64.1%)

 

Arab-American

94

(1%)

25

(26.6%)

69

(73.4%)

 

Hispanic

 

1,415

(15.5%)

648

(45.8%)

767

 

Asian

449

(4.9%)

162

(36.1%)

287

(63.9%)

 

American Indian/Alaskan

19

(0.2%)

8

(42.1%)

11

(57.9%)

 

Other

6

(0.07%)

1

(16.7%)

5

(83.3%)

 

Unknown

32

(0.35%)

13

(40.6%)

19

(59.4%)

Estrogen Receptor a

 

Positive

3,258

(37.9%)

893

(33.8%)

2,365

(39.7%)

<0.0001

 

Negative

2,909

(33.8%)

1,017

(38.4%)

1,892

(31.7%)

 

Unknown

2,438

(28.3%)

735

(27.8%)

1,703

(28.6%)

Progesterone Receptor a

 

Positive

2,551

(29.7%)

768

(29.0%)

1,783

(29.9%)

0.17

 

Negative

3,480

(40.4%)

1,109

(41.9%)

2,371

(39.8%)

 

Unknown

2,574

(29.9%)

768

(29.0%)

1,806

(30.3%)

Her-2 Receptor b

 

Positive

1,042

(23.6%)

349

(27.3%)

693

(22.1%)

0.0005

 

Negative

1,496

(33.9%)

426

(33.4%)

1,070

(34.1%)

 

Unknown

1,879

(42.5%)

502

(39.3%)

1,377

(43.8%)

Education c

 

High

2,801

(30.7%)

814

(29.0%)

1,987

(31.4%)

<0.0001

 

Middle

2,702

(29.6%)

756

(26.9%)

1,946

(30.8%)

 

Low

3,632

(39.8%)

1,241

(44.2%)

2,391

(37.8%)

% No Education c

 

22.1

(17)

24.1

(18.4)

21.2

(16.3)

<0.0001

Age at diagnosis

 

58.1

(14.7)

41.7

(5.8)

65.4

(11.2)

<0.0001

Survival time in months

 

46.5

(122.2)

96.4

(77.3)

59.2

(61.1)

<0.0001

  1. a Sample size for ER and PR for cases diagnosed 1990–2008 only (IBC=8,605, pre-menopause=2,645, post-menopause =5,960)).
  2. b Sample size for HER2 for cases diagnosed 1999–2008 (IBC=4,417, pre-menopause=1,277, post-menopause =3,140).
  3. c % No Education (25 years of age or older without a high school diploma) and Education (tertiles of distribution) based on census tract-level information.
  4. * ANOVA test for continuous variables, chi-sq for categorical (or Fisher's exact test for cell counts <5), log-rank test for Survival. All statistical tests comparing differences in premenopausal and postmenopausal IBC cases.