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Table 9 Multivariate analysis for breast-cancer survival

From: Succinate dehydrogenase expression in breast cancer

Parameters Disease-free survival Overall survival
Hazard ratio 95% CI P-value Hazard ratio 95% CI P-value
T stage    0.003    0.008
 T1 versus T2-3 2.535 1.376 − 4.670   2.218 1.229 − 4.001  
N stage    0.002    0.026
 N0 versus N1-3 2.257 1.335 − 3.816   1.831 1.076 − 3.115  
Histologic grade    0.045    0.372
 I/II versus III 1.685 1.013 − 2.804   1.276 0.748 − 2.176  
Nuclear HIF-1α    0.599    0.486
 Negative versus Positive 0.682 0.163 − 2.846   0.599 0.142 − 2.528  
Tumor SDHA    0.290    0.002
 Negative/Low versus High 1.570 0.681 − 3.620   4.157 1.657 − 10.432  
Stromal SDHA    0.727    0.747
 Negative versus Positive 1.254 0.352 − 4.468   0.807 0.218 − 2.978  
Tumor SDHB    0.096    0.012
 Negative/Low versus High 0.498 0.219 − 1.131   3.223 1.295 − 8.025  
Stromal SDHB    0.712    0.965
 Negative versus Positive 0.802 0.248 − 2.590   0.976 0.327 − 2.908  
  1. SDH succinate dehydrogenase.