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Table 3 Systemic therapy for pregnancy associated breast cancer

From: Contemporary multidisciplinary treatment of pregnancy-associated breast cancer

Systemic therapy (N = 68 patients delivered live born infants, 36 received chemotherapy therapy) Number Percent
 Chemotherapy during pregnancy (N = 68)   
 Yes 36 52.9
 No 32 47.1
Gestational age at initiation of treatment (N = 36)   
 0-12 weeks (1st trimester) 0 0.0
 13-27 weeks (2nd trimester) 29 80.6
 28-40 weeks (3rd trimester) 7 19.4
Chemotherapy regimen (N = 36)   
 Every-3-week AC 29 80.6
    4 cycles 21 72.4
    3 cycles 2 6.9
    2 cycles 5 17.2
    1 cycle 1 3.4
 Dose-dense AC 7 19.4
    4 cycles 5 71.4
    2 cycles 2 28.6
 AC × 4 + weekly paclitaxel (12 weeks) 3 8.3
   Dose-dense AC 2 66.6
   Every-3-week AC 1 33.4
Neoadjuvant chemotherapy (N = 36)   
 Yes 8 22.2
Growth factor support (N = 36)   
 Yes 6 16.7
   Pegfilgrastim 4 66.7
   Filgrastim 2 33.3
  1. Abbreviations: AC doxorubicin, cyclophosphamide.