Table 1 Data of mean glucose unit (GU) value, tentative structure assignment, and relative (%) area of the peaks of the monoclonal antibody produced by CHO-K1 cells under different culture conditions: T-Flask; CYi – Cytodex 3 in vented conical tubes; CYS – Cytodex 3 in shake flask

1

4.9 ± 0.01

2.09

3.33

3.54

3.03

3.76

10.54

4.48

1.77

6.10

2

5.33 ± 0.01

2.01

1.75

1.59

2.54

3.03

3.40

1.56

1.74

3.32

3

5.66 ± 0.01

-

5.69

5.76

5.15

5.31

14.16

5.70

-

8.60

4

5.80 ± 0.01

40.99

22.01

16.59

20.59

21.24

16.93

16.87

30.92

27.57

5

6.18 ± 0.01

1.50

1.93

1.68

2.44

2.39

3.13

1.77

2.45

2.82

6

6.31 ± 0.04

-

1.61

1.19

1.97

2.55

-

1.36

1.29

4.86

7

6.42 ± 0.01

-

2.34

2.49

1.82

1.88

6.22

2.77

-

-

8

6.64 ± 0.01

23.52

20.74

15.60

16.12

17.10

13.20

15.62

25.59

23.46

9

6.75 ± 0.01

9.11

15.18

10.53

11.45

12.98

7.33

11.77

13.23

9.85

10

7.15 ± 0.02

1.65

2.59

2.15

1.94

2.37

3.25

2.72

1.81

2.59

11

7.59 ± 0.01

8.40

14.65

11.74

9.86

11.60

7.76

12.61

13.43

9.27

12

7.97 ± 0.01

2.73

2.16

2.18

1.91

1.83

2.86

2.54

1.72

1.56

13

8.46 ± 0.01

0.91

1.29

2.12

2.03

1.58

2.44

1.98

1.09

-

14

8.70 ± 0.02

-

-

-

-

-

0.85

1.08

-

-

15

8.88 ± 0.01

0.98

1.26

2.38

2.19

1.71

0.78

1.68

1.06

-

16

9.17 ± 0.02

-

-

-

-

-

-

-

-

-

17

9.36

-

-

-

-

-

-

-

-

-

18

9.58 ± 0.01

1.99

0.73

3.70

2.31

1.88

1.95

2.64

0.94

-

19

10.03 ± 0.01

0.95

1.25

6.43

5.66

3.17

2.84

4.94

1.54

-

20

10.22 ± 0.00

-

-

1.18

1.11

0.54

-

1.04

-

-

21

10.43 ± 0.01

1.14

1.49

4.56

5.85

3.73

2.35

5.08

1.40

-

22

10.56 ± 0.01

-

-

2.05

-

-

-

-

-

-

23

10.68

0.92

-

-

-

-

-

-

-

-

24

10.93 ± 0.04

0.84

-

2.54

2.01

1.34

-

1.79

-

-

25

11.12 ± 0.01

-

-

-

-

-

-

-

-

-

26

11.43

0.27

-

-

-

-

-

-

-

-

82.02

72.58

54.46

58.02

62.92

45.22

56.87

83.17

70.15

17.98

27.42

45.54

41.96

37.07

54.77

43.13

16.81

29.85