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Table 1 Characterization of the autopsy cases

From: hTERT promoter polymorphism, -1327C>T, is associated with the risk of epithelial cancer

Clinical features

Controla (n = 591)

Cases with malignancy (n = 960)

Total (n = 1551)

p-value

Age (years, average ± SD)

81.4 ± 9.2

79.6 ± 8.6

80.3 ± 8.9

0.0001b

Male/Female ratio

0.98

1.34

1.19

0.0031c

Smoker / Totald

0.45

0.51

0.49

0.028c

Alcohol drinker / Totale

0.23

0.27

0.25

0.074c

  1. aCases with no malignancy.
  2. bp-value based on one-way ANOVA.
  3. cp-value based on chi-square analysis.
  4. dCalculated for cases whose smoking history was available (n = 1391). Smokers were defined as those who smoked one or more cigarettes per day.
  5. eCalculated for cases whose drinking history was available (n = 1433). Alcohol drinkers were defined as those who consumed 15 grams or more alcohol per day.