Table 1 The list of overexpressed genes in three classes of lung tumors (SCLC, NSCLC and COMMON) defined by microarray analysis; extracted from GSEA db
From: Prediction of lung tumor types based on protein attributes by machine learning algorithms
Tumor type | Gene Symbol |
|---|---|
SCLC | APAF1, BCL2, BCL2L1, BIRC2, BIRC3, CCNE1, CCNE2, CDK2, CDKN1B, CDKN2B, CHUK, CKS1B, COL4A1, COL4A2, COL4A4, COL4A6, CYCS, FN1, IKBKB, IKBKG, ITGA2, ITGA2B, ITGA3, ITGA6, ITGAV, ITGB1, LAMA1, LAMA2, LAMA3, LAMA4, LAMA5, LAMB1, LAMB2, LAMB3, LAMB4, LAMC1, LAMC2, LAMC3, MAX, MYC, NFKB1, NFKBIA, NOS2, PIAS1, PIAS2, PIAS3, PIAS4, PTEN, PTGS2, PTK2, RELA, SKP2, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, XIAP |
NSCLC | ARAF, BAD, BRAF, CDKN2A, EGF, EGFR, ERBB2, FOXO3, GRB2, HRAS, KRAS, MAP2K1, MAP2K2, MAPK1, MAPK3, NRAS, PDPK1, PLCG1, PLCG2, PRKCA, PRKCB, PRKCG, RAF1, RASSF1, RASSF5, SOS1, SOS2, STK4, TGFA |
COMMON | AKT1, AKT2, AKT3, CASP9, CCND1, CDK4, CDK6, E2F1, E2F2, E2F3, FHIT, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIK3R3, PIK3R5, RARB, RB1, RXRA, RXRB, RXRG, TP53 |