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Figure 1 | SpringerPlus

Figure 1

From: A Phase I, open-label, randomized, crossover study in three parallel groups to evaluate the effect of Rifampicin, Ketoconazole, and Omeprazole on the pharmacokinetics of THC/CBD oromucosal spray in healthy volunteers

Figure 1

Mean (+ SD ) plasma concentrations of THC ( a ), CBD (b) and 11-OH-THC ( c ) over time after administration of a single dose ( 4 sprays ) of THC/ CBD ( n = 11 ) or THC/ CBD spray in combination with multiple dose ( 2 x 300 mg ) administration of Rifampicin ( n = 12 ) .

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