Table 3 Normalized data of type-I-interferon expression after siRNA - mediated inhibition of gene expression of potential DNA receptors in HaCaT cells and HKC ([siRNA - Efficiency (Expression in % of control)/type-I-IFN expression (Expression in % of control)] ± SEM)
AIM2 | NALP3 | mda5 | DAI | |||||
|---|---|---|---|---|---|---|---|---|
HaCaT | HKC | HaCaT | HKC | HaCaT | HKC | HaCaT | HKC | |
IFN-alpha | 0,79± | 0,75± | 1,29± | 0,88± | 0,81± | 0,71± | 1,14± | 0,92± |
0,15 | 0,12 | 0,12 | 0,15 | 0,07 | 0,03 | 0,04 | 0,11 | |
IFN-beta | 0,98± | 1,27± | 0,72± | 0,70± | 0,60± | 0,82± | 1,07± | 0,83± |
0,02 | 0,65 | 0,01 | 0,07 | 0,03 | 0,3 | 0,09 | 0,03 | |