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Figure 5 | SpringerPlus

Figure 5

From: Innate immune response after adenoviral gene delivery into skin is mediated by AIM2, NALP3, DAI and mda5

Figure 5

siRNA-mediated inhibition of gene expression. (A) Efficiency of siRNA - mediated inhibition of gene expression. Expression of AIM2, NALP3, mda5 and DAI mRNA in HaCaT cells and HKC 48 h after siRNA transfection (* = p <0.05, ** = p <0.005). (B) Effects of siRNA - mediated inhibition of potential receptor gene expression. Expression of type-I-interferon (x-fold in relation to a vehicle control) after siRNA-mediated inhibition of potential DNA receptor mRNA expression. Two days after silencing, cells were transfected with 5 μg/ml isolated adenoviral DNA for 15 h (HaCaT) or 6 h (HKC) (* = p <0.05).

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