|  | Penetrance of genotype |  |
---|
 |
CC
|
Cc
|
cc
|
---|
Genotype |
BB
|
Bb
|
bb
|
BB
|
Bb
|
bb
|
BB
|
Bb
|
bb
|
---|
AA
| 0 | 0 | 16K
| 0 | 0 | 0 | 0 | 0 | 0 |
Aa
| 0 | 0 | 0 | 0 | 4K
| 0 | 0 | 0 | 0 |
aa
| 0 | 0 | 0 | 0 | 0 | 0 | 16K
| 0 | 0 |
-
AA, BB and CC denote homozygous wild-type genotypes. Aa, Bb and Cc denote heterozygous genotypes. aa, bb and cc denote homozygous variant genotypes. All allele frequencies are equal (p
A
= p
B
= p
C
= 0.5). K = 1/901.