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Table 5 Inflammation and oxidative stress markers in both arms

From: Long-term, up to 18 months, protective effects of the angiotensin II receptor blocker telmisartan on Epirubin-induced inflammation and oxidative stress assessed by serial strain rate

Parameters t0(n = 49) t2(n = 49) t3(n = 49) t4(n = 49) 12-Month FU (n = 44) 18-Month FU (n = 44) P - value (ANOVA test)
TNFα
 PLA 30.1 ± 9.0 47.1 ± 4.6 30.0 ± 14.4 25.8 ± 8.6 30.0 ± 14.4 8.3 ± 8.4 0.32
 TEL 23.5 ± 5.5 22.3 ± 10.6 35.1 ± 8.6 25.9 ± 4.2 35.1 ± 8.6 12.1 ± 2.9 0.56
GPx
 PLA 7.386 ± 3.041 6.898 ± 1.552 9.427 ± 3.078 10.232 ± 1.875 9.427 ± 3.078 11669 ± 3336 0.56
 TEL 7.415 ± 2.182 6.381 ± 2.137 7.263 ± 2.998 7.479 ± 1.769 7.263 ± 2.998 8507 ± 2316 0.88
SOD
 PLA 130.0 ± 9.2 138.0 ± 2.1 193.0 ± 41.0 148.0 ± 38.0 135.0 ± 26.0 134 ± 31 0.32
 TEL 126.1 ± 41.6 150.0 ± 37.0 140.0 ± 40.0 145.0 ± 74.0 150.0 ± 37.0 169.5 ± 70 0.95
  1. TNF, tumor necrosis factor; GPx, glutathione peroxidase; SOD, superoxide dismutase.