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Table 5 Inflammation and oxidative stress markers in both arms

From: Long-term, up to 18 months, protective effects of the angiotensin II receptor blocker telmisartan on Epirubin-induced inflammation and oxidative stress assessed by serial strain rate

Parameters

t0(n = 49)

t2(n = 49)

t3(n = 49)

t4(n = 49)

12-Month FU (n = 44)

18-Month FU (n = 44)

P - value (ANOVA test)

TNFα

 PLA

30.1 ± 9.0

47.1 ± 4.6

30.0 ± 14.4

25.8 ± 8.6

30.0 ± 14.4

8.3 ± 8.4

0.32

 TEL

23.5 ± 5.5

22.3 ± 10.6

35.1 ± 8.6

25.9 ± 4.2

35.1 ± 8.6

12.1 ± 2.9

0.56

GPx

 PLA

7.386 ± 3.041

6.898 ± 1.552

9.427 ± 3.078

10.232 ± 1.875

9.427 ± 3.078

11669 ± 3336

0.56

 TEL

7.415 ± 2.182

6.381 ± 2.137

7.263 ± 2.998

7.479 ± 1.769

7.263 ± 2.998

8507 ± 2316

0.88

SOD

 PLA

130.0 ± 9.2

138.0 ± 2.1

193.0 ± 41.0

148.0 ± 38.0

135.0 ± 26.0

134 ± 31

0.32

 TEL

126.1 ± 41.6

150.0 ± 37.0

140.0 ± 40.0

145.0 ± 74.0

150.0 ± 37.0

169.5 ± 70

0.95

  1. TNF, tumor necrosis factor; GPx, glutathione peroxidase; SOD, superoxide dismutase.