Table 7 Predicted ligand binding site of CAS and β-AS using Q-SiteFinder
Cycloartenol synthase | β-amyrin synthase | ||
|---|---|---|---|
Residues | Residue number | Residues | Residue number |
TYR | 118 | PRO | 124 |
PRO | 121 | PHE | 127 |
LEU | 124 | TRP | 258 |
TRP | 255 | CYS | 259 |
CYS | 256 | TYR | 260 |
HIS | 257 | ILE | 368 |
CYS | 258 | GLY | 369 |
ILE | 365 | CYS | 370 |
GLY | 366 | VAL | 771 |
PRO | 367 | GLN | 411 |
VAL | 368 | SER | 412 |
GLY | 409 | TRP | 418 |
TYR | 410 | PHE | 474 |
TRP | 479 | VAL | 483 |
ILE | 481 | ASP | 485 |
THR | 531 | CYS | 486 |
TYR | 532 | ILE | 534 |
GLU | 533 | TRP | 535 |
PHE | 550 | CYS | 565 |
ILE | 553 | TRP | 613 |
ASP | 556 | TYR | 619 |
TYR | 559 | *VAL | *728 |
SER | 609 | TYR | 729 |
TRP | 610 | LEU | 735 |
VAL | 725 | TYR | 737 |
PHE | 726 | TYR | 740 |
ASN | 727 | ||
*LYS | *728 | ||
CYS | 730 | ||
ILE | 732 | ||