Drug (μg/ml)
|
Before treatment
|
3 min after treatment
|
5 min after treatment
|
---|
M1
|
MX
|
R (%)
|
M1
|
MX
|
R (%)
|
M1
|
MX
|
R (%)
|
---|
Rocuronium 2.5
|
46 ± 11
|
34 ± 10
|
26
|
46 ± 10
|
28 ± 10
|
40*
|
45 ± 12
|
26 ± 10*
|
42*
|
Vecuronium 0.5
|
46 ± 11
|
33 ± 11
|
28
|
46 ± 11
|
31 ± 10
|
33
|
45 ± 12
|
29 ± 11*
|
37*
|
-
*
P < 0.05, compared with the corresponding group without drug treatment; n = 5. M1, the first quantum content of EPP; MX, the 11 to 55 average quantum content of EPP; R, the rundown rate. M = Vc/q; Vc is the corrected amplitude of EPP and q is the quantum size of the MEPP. Data shown are means ± SEM.