Vecuronium (μg/ml)
|
EPP (mV) before administration
|
EPP (mV) at different times after treatment
|
---|
3 min
|
5 min
|
10 min
|
---|
Control
|
32.4 ± 3.3
|
32.2 ± 3.3
|
31.4 ± 3.2
|
31.2 ± 2.9
|
0.5
|
32.3 ± 3.4
|
31.7 ± 2.9
|
30.6 ± 3.3
|
29.7 ± 2.2
|
1.0
|
31.5 ± 3.2
|
27.4 ± 2.7
|
22.4 ± 2.8*
|
16.4 ± 2.1**##
|
2.0
|
33.1 ± 3.4
|
22.4 ± 3.3*#
|
14.4 ± 1.4**##
|
12.4 ± 1.3**##
|
4.0
|
32.7 ± 3.1
|
18.4 ± 3.3**##
|
12.4 ± 1.5**##
|
8.4 ± 1.3**##
|
-
*
P < 0.05, **
P < 0.01, compared with the corresponding group without vecuronium; #
P < 0.05, ##
P < 0.01, compared with the control at the same time point; n = 5. Data shown are means ± SEM.