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Table 1 Effects of rocuronium on the amplitude of endplate potentials (EPPs) in the isolated rat phrenic nerve diaphragm preparation at different time points after treatment

From: Effects of rocuronium and vecuronium on initial rundown of endplate potentials in the isolated phrenic nerve diaphragm preparation of rats

Rocuronium (μg/ml) EPP (mV) before treatment EPP (mV) at different times after treatment
1 min 3 min 5 min
Control 32.4 ± 3.3 32.2 ± 3.4 32.2 ± 3.3 31.4 ± 3.5
2.5 32.6 ± 3.6 32.3 ± 3.4 32.1 ± 3.5 31.2 ± 3.3
5.0 33.5 ± 3.4 32.4 ± 3.3 22.4 ± 2.9*# 14.6 ± 2.1**##
10.0 34.8 ± 4.3 27.2 ± 2.5** 16.4 ± 1.3**## 12.4 ± 1.3**##
20.0 33.2 ± 3.1 22.4 ± 2.3*# 12.4 ± 2.3*# 9.4 ± 1.1**##
  1. * P < 0.05, ** P < 0.01, compared with the corresponding group without rocuronium; # P < 0.05, ## P < 0.01, compared with the control at the same time point; n = 5. Data shown are means ± SEM.