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Table 1 Summary of immunohistochemistry

From: Rare case of malignant transformation of recurrent respiratory papillomatosis associated with human papillomavirus type 6 infection and p53 overexpression

  A B C D E F
HE dysplasia dysplasia dysplasia dysplasia dysplasia SCC
p16 mild mild moderate moderate strong negative
p53 mild mild mild mild mild strong
EGFR strong strong strong strong strong strong
pEGFR      positive negative
pERK      positive negative
  1. Specimens obtained from the larynx in 1989 (A), 1994 (B), 2000 (C), 2005 (D), and 2011 (E), and on the tumor tissue obtained from around the tracheotomy aperture in 2011 (F).