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Table 1 Summary of immunohistochemistry

From: Rare case of malignant transformation of recurrent respiratory papillomatosis associated with human papillomavirus type 6 infection and p53 overexpression

	A	B	C	D	E	F
HE	dysplasia	dysplasia	dysplasia	dysplasia	dysplasia	SCC
p16	mild	mild	moderate	moderate	strong	negative
p53	mild	mild	mild	mild	mild	strong
EGFR	strong	strong	strong	strong	strong	strong
pEGFR					positive	negative
pERK					positive	negative

Specimens obtained from the larynx in 1989 (A), 1994 (B), 2000 (C), 2005 (D), and 2011 (E), and on the tumor tissue obtained from around the tracheotomy aperture in 2011 (F).

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