Table 1 Comparison of clinicopathological features between the 2 groups
Variable | Hypermethylation group n = 22 (%) | Hypomethylation group n = 66 (%) | P | |
|---|---|---|---|---|
Gender | M | 17 (77.3) | 58 (87.9) | 0.225 |
F | 5 (22.7) | 8 (12.1) | ||
Age (y)a | 65.8 (50.0-78.0) | 68.5 (50.0-78.0) | 0.07 | |
ICG15R (%) | < 10 | 6 (27.3) | 26 (39.4) | 0.306 |
≧10 | 16 (72.7) | 40 (60.6) | ||
Alb (g/dl) | < 3.5 | 9 (40.9) | 6 (9.1) | 0.001 |
≧3.5 | 13 (59.1) | 60 (90.9) | ||
AST (U/l) | < 40 | 7 (31.8) | 21 (31.8) | 1.000 |
≧40 | 15 (68.2) | 45 (68.2) | ||
ALT (U/l) | < 40 | 9 (40.9) | 27 (40.9) | 1.000 |
≧40 | 13 (59.1) | 39 (59.1) | ||
T.Bil (mg/dl) | < 1.2 | 20 (90.9) | 59 (89.4) | 0.839 |
≧1.2 | 2 (9.1) | 7 (10.6) | ||
AFP (ng/ml) | < 20 | 8 (36.4) | 42 (63.6) | 0.018 |
≧20 | 14 (63.6) | 24 (36.4) | ||
non-LC | 10 (45.5) | 41 (62.1) | 0.170 | |
LC | 12 (54.5) | 25 (37.9) | ||
Vascular invasion | (+) | 10 (45.5) | 43 (65.2) | 0.102 |
(−) | 12 (54.5) | 23 (34.8) | ||
Tumor multiplicity | single | 22 (100) | 54 (81.8) | 0.031 |
multiple | 0 (0) | 12 (18.2) | ||
Liver damage | A | 15 (68.2) | 38 (57.6) | 0.379 |
B | 7 (31.8) | 28 (42.4) | ||
Recurrence | (+) | 19 (86.4) | 52 (78.8) | 0.436 |
(−) | 3 (13.6) | 14 (21.2) |