Figure 3
The triplet ITL (dark-shaded letters) during the evolution of GABAB1 subunit: CAEEL (Caenorhabditis elegans), LOUSE(Pediculus humanus corporis), DROPS(Drosophila pseudoobscura), ANOGA(Anopheles gambiae), DANRE(Danio rerio), TETNG(Tetraodon nigroviridis), FROG(Xenopus tropicalis), RAT(Rattus norvegicus), MOUSE(Mus musculus), and HUNAN(Homo sapiens); asterisk (*) marks homologies (F and L); quote (') marks leucine-like homologies (L and I); bold letters are main players of leucine-rich motifs (L, S, and C).