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Table 1 Pharmacokinetics of tamoxifen, letrozole and anastrozole before and after treatment with ginkgo biloba (GB)

From: Investigation of herb-drug interactions with ginkgo biloba in women receiving hormonal treatment for early breast cancer

Drug Drug trough concentration (ng/mL) before GB treatment Drug trough concentration (ng/mL) during GB treatment P-value*
Tamoxifen (N=20) 93.5 ± 29.0 86.5 ± 25.3 P = 0.16
Letrozole (N =20) 91.1 ± 50.4 89.6 ± 52.14 P = 0.60
Anastrozole (N =20) 29.1 ± 8.6 29.1 ±7.6 P =0.97
  1. *paired test; data presented as mean ± standard deviation.