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Table 1 Pharmacokinetics of tamoxifen, letrozole and anastrozole before and after treatment with ginkgo biloba (GB)

From: Investigation of herb-drug interactions with ginkgo biloba in women receiving hormonal treatment for early breast cancer

Drug

Drug trough concentration (ng/mL) before GB treatment

Drug trough concentration (ng/mL) during GB treatment

P-value*

Tamoxifen (N=20)

93.5 ± 29.0

86.5 ± 25.3

P = 0.16

Letrozole (N =20)

91.1 ± 50.4

89.6 ± 52.14

P = 0.60

Anastrozole (N =20)

29.1 ± 8.6

29.1 ±7.6

P =0.97

  1. *paired test; data presented as mean ± standard deviation.
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