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Table 1 In vitro cytotoxicity of bioactive compounds produced by Chrysosporium lobatum strain BK-3

From: Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India

Compounds IC50values (μM) (Mean ± S.D.b)
  MCF-7 A549 MDA-MB-231 COLO 205 K562 HeLa HEK293 (normal)
α, β-Dehydrocurvularin 11.19 ± 0.31 2.10 ± 0.33 9.34 ± 0.38 7.9 ± 0.09 a 21.01 ± 0.19
Curvularin 21.89 ± 0.19 13.91 ± 0.15 1.3 ± 0.37 25.64 ± 0.37
Doxorubicin (Standard) 1.05 ± 0.37 1.21 ± 0.41 0.501 ± 0.26 0.985 ± 0.33 0.318 ± 0.26 0.451 ± 0.25
  1. a– No activity; bS.D.: Standard deviation.