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Table 1 In vitro cytotoxicity of bioactive compounds produced by Chrysosporium lobatum strain BK-3

From: Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India

Compounds

IC50values (μM) (Mean ± S.D.b)

 

MCF-7

A549

MDA-MB-231

COLO 205

K562

HeLa

HEK293 (normal)

α, β-Dehydrocurvularin

11.19 ± 0.31

2.10 ± 0.33

9.34 ± 0.38

7.9 ± 0.09

–a

21.01 ± 0.19

–

Curvularin

21.89 ± 0.19

13.91 ± 0.15

1.3 ± 0.37

–

–

25.64 ± 0.37

–

Doxorubicin (Standard)

1.05 ± 0.37

1.21 ± 0.41

0.501 ± 0.26

0.985 ± 0.33

0.318 ± 0.26

0.451 ± 0.25

–

  1. a– No activity; bS.D.: Standard deviation.
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