Figure 2From: Structure-activity-relationship study of N-acyl-N-phenylpiperazines as potential inhibitors of the Excitatory Amino Acid Transporters (EAATs): improving the potency of a micromolar screening Hit is not truism Chemical structure of screening hit N -acyl- N -phenylpiperazine (±)-exo-1 displaying inhibitory activity at EAAT1-3 in the mid-micromolar range (IC 50 = 10, 40 and 30 μ M, respectively). Back to article page