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Table 2 Patient and tumor characteristics for the case–control study (Patient material VI (Ahlin et al. 2009)

From: The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer

Factor   Patient material VI
   Case Control
No of patients 166 166
Age median, years 69 61
Age range, years 34-88 32-89
Tumor size   
  ≤ 20 mm 102 (61)a 131 (79)
  >20 mm 64 (39) 35 (21)
Lymph nodes   
  Negative 166 166
ER status   
  Positive 94 (57) 131 (79)
  Negative 72 (43) 35 (21)
PgR status   
  Positive 69 (42) 113 (68)
  Negative 96 (58) 53 (32)
  Missing 1 0
Histological grade   
  1 14 (8) 39 (23)
  2 85 (51) 94 (57)
  3 67 (41) 33 (20)
Ki67   
  Low 87 (52) 112 (67)
  Highb 79 (48) 54 (33)
HER2 status   
  Negative 145 (91) 143 (92)
  Positivec 14 (9) 13 (8)
  Missing 7 10
Adjuvant endocrine treatment
  Yes 48 (29) 40 (24)
  No 118 (71) 126 (76)
  1. ER = estrogen receptor, PgR = progesterone receptor, HER2 = human epidermal growth factor 2.
  2. aNumbers in parentheses are percentages.
  3. bHigh Ki67 was defined as cases with more than 20% positive cells.
  4. cHER2: positive if HER2-IHC 3+ or HER2-IHC 2+ and FISH amplified.