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Table 2 Patient and tumor characteristics for the case–control study (Patient material VI (Ahlin et al. 2009)

From: The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer

Factor

 

Patient material VI

  

Case

Control

No of patients

166

166

Age median, years

69

61

Age range, years

34-88

32-89

Tumor size

  
 

≤ 20 mm

102 (61)a

131 (79)

 

>20 mm

64 (39)

35 (21)

Lymph nodes

  
 

Negative

166

166

ER status

  
 

Positive

94 (57)

131 (79)

 

Negative

72 (43)

35 (21)

PgR status

  
 

Positive

69 (42)

113 (68)

 

Negative

96 (58)

53 (32)

 

Missing

1

0

Histological grade

  
 

1

14 (8)

39 (23)

 

2

85 (51)

94 (57)

 

3

67 (41)

33 (20)

Ki67

  
 

Low

87 (52)

112 (67)

 

Highb

79 (48)

54 (33)

HER2 status

  
 

Negative

145 (91)

143 (92)

 

Positivec

14 (9)

13 (8)

 

Missing

7

10

Adjuvant endocrine treatment

 

Yes

48 (29)

40 (24)

 

No

118 (71)

126 (76)

  1. ER = estrogen receptor, PgR = progesterone receptor, HER2 = human epidermal growth factor 2.
  2. aNumbers in parentheses are percentages.
  3. bHigh Ki67 was defined as cases with more than 20% positive cells.
  4. cHER2: positive if HER2-IHC 3+ or HER2-IHC 2+ and FISH amplified.