RNA blood levels of osteopontin splice variants are cancer markers

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Table 3 Cancer stage and primary tumor size

To determine the relationship between osteopontin splice variant levels and tumor stage or primary tumor size, Spearman’s correlation coefficient and its associated p-value were calculated. For lung cancers (A), stage I-IV was used (n = 10, 6, 11, 6 for I, II, II, IV). For breast cancers (B), stage T (n = 37, 16, 8, 2 for T1, T2, T3, T4) and N (n = 28, 20, 5, 7, 0 for N0, N1, N2, N3, N4) were applied to the analysis. Of note, the significant p-value is not reflective of a strong correlation. It indicates that the population correlation coefficient is different than zero with the degree of confidence given by the p-value.