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Table 3 Cancer stage and primary tumor size

From: RNA blood levels of osteopontin splice variants are cancer markers

A. lung cancer     
lung cancer stage   OPNa OPNb OPNc
  correlation coefficient 0.127 0.172 0.185
  p-value 0.480 0.339 0.304
lung cancer size   OPNa OPNb OPNc
  correlation coefficient -0.193 -0.508 -0.012
  p-value 0.259 0.002 0.942
B. breast cancer     
breast cancer stage T   OPNa OPNb OPNc
  correlation coefficient 0.223 0.123 0.087
  p-value 0.084 0.343 0.507
breast cancer stage N   OPNa OPNb OPNc
  correlation coefficient 0.078 -0.084 0.161
  p-value 0.561 0.530 0.227
breast cancer size   OPNa OPNb OPNc
  correlation coefficient -0.070 -0.090 0.111
  p-value 0.585 0.480 0.385
  1. To determine the relationship between osteopontin splice variant levels and tumor stage or primary tumor size, Spearman’s correlation coefficient and its associated p-value were calculated. For lung cancers (A), stage I-IV was used (n = 10, 6, 11, 6 for I, II, II, IV). For breast cancers (B), stage T (n = 37, 16, 8, 2 for T1, T2, T3, T4) and N (n = 28, 20, 5, 7, 0 for N0, N1, N2, N3, N4) were applied to the analysis. Of note, the significant p-value is not reflective of a strong correlation. It indicates that the population correlation coefficient is different than zero with the degree of confidence given by the p-value.