Table 3 Comparison of characteristics of various mushroom ribonucleases
From: First biochemical characterization of a novel ribonuclease from wild mushroom Amanita hemibapha
Mol mass (kDa) | Optimum pH | Optimum temperature | HIV-1 RT inhibitory activity (IC50 in μM) | Antiproliferative activity (IC50 in μM) | |||
|---|---|---|---|---|---|---|---|
L1210 cells | Hep G2 cells | MCF-7 cells | |||||
A. hemibapha | 45 | 5.0 | 60~70 | 17 | ND | UD | UD |
Boletus griseus | 29 | 3.5 | 60-70 | ND | ND | ND | ND |
Clitocybe maxima | 17.5 | 6.5, 7.0 | 70 | ND | ND | ND | ND |
Dictyophora indusiata | 28 | 4-4.5 | 60 | ND | ND | ND | ND |
Ganoderma lucidum | 42 | 4 | 60 | ND | ND | ND | ND |
Hypsizigus marmoreus | 18 | 5 | 70 | ND | 60 | ND | ND |
Lyophyllum shimeiji | 14.5 | 6 | 70 | 7.2 | ND | 10 | 6.2 |
Pleurotus djamor | 15 | 4.6 | 60 | ND | ND | 3.9 | 3.4 |
Pleurotus eryngii | 16 | 6.5 | 70 | ND | ND | ND | ND |
Pleurotus ostreatus (Nomura et al.) | 12.4 | 8.0 | ND | ND | ND | ND | ND |
Pleurotus ostreatus (Ye et al.) | 12 | 7.0 | 40 | ND | ND | ND | ND |
Pleurotus pulmonarius | 14.4 | 7 | 55 | ND | ND | ND | ND |
Pleurotus sajor-caju | 12 | 5.5 | <60 | ND | 0.1 | 0.22 | ND |
Pleurotus tuber-regium | 29 | 6.5 | ND | ND | ND | ND | ND |
Russula delica | 14 | 5 | 60 | UD | ND | 8.6 | 7.2 |
Russulus virescens | 28 | 4.5 | 60 | ND | ND | ND | ND |
Thelephora ganbajun | 30 | 6-7 | 40 | 0.3 | ND | ND | ND |
Volvariella volvacea | 42.5 | 6.5,-7.5 | ND | ND | ND | ND | ND |