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Figure 1

From: Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway

Figure 1

HCT116 cells are sensitive to FCdR treatment. A. HCT116, HepG2, U2OS and KYSE150 cell lines were treated with FCdR at indicated concentrations for 72 h and MTT assays performed. HCT116 cells were the most sensitive to FCdR. B. Four inhibitors against epigenetic enzymes were used to treat HCT116 cells for 72 h, and MTT assay performed to test their toxicity. HCT116 cells were more sensitive to FCdR and SAHA, compared to 5-azaC and BIX01294. (* p value < 0.05; ** p value < 0.01).

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