Figure 2

Histopathology of group 1. Case T-4 exhibits very severe full-thickness necrotizing enteritis (Figures 2A-D). The most severely damaged tissue is shaped like an erupting volcano (Figure 2A, arrow). Other areas are irregularly shaped. Erosion, ulceration, and granulation (g) are seen (Figures 2B and C). Intestinal epithelial cells and crypt(c) structure disappear or are modified by inflammation and organization (Figures 2B-D). Neutrophils are the predominant infiltrating cells (Figure 2C). Edema of the muscle layer (m) is observed (Figures 2A and B). Medium infiltration and edema in the lamina propria mucosa and sub-mucosa (sm) are observed to vary by area (Figure 2D). Erosion and ulceration are seen in T2 (Figure 2E) and 3 (Figure 2F). Crypt (c) structure is irregularly shaped or disappears due to inflammation and granulation (g) (Figures 2E and F).