Skip to main content
SpringerPlus

Table 1 Endocytosis related gene expression analysis in the MALME-3M cell line after treatment with albumin-associated lipids

From: Transdifferentiation of MALME-3M and MCF-7 Cells toward Adipocyte-like Cells is Dependent on Clathrin-mediated Endocytosis

GENE SYMBOL

GENE DESCRIPTION

ENSEMBL ID

FOLD CHANGE

CLTC

clathrin, heavy chain (Hc)

ENSG00000141367

1.46

TFRC

transferring receptor (p90, CD71)

ENSG00000072274

3.33

AP1B1

adaptor-related protein complex 1, beta 1 subunit

ENSG00000100280

1.62

AP1G1

adaptor-related protein complex 1, gamma 1 subumit

ENSG00000166747

1.53

AP1S3

adaptor-related protein complex 1, sigma 3 subunit

ENSG00000152056

2.29

AP2A1

adaptor-related protein complex 2, alpha 1 subunit

ENSG00000196961

1.83

SYNRG

synergin gamma or AP1 gamma subunit binding protein 1

ENSG00000006114

1.26

AP3M1

adaptor-related protein complex 3, mu 1 subunit

ENSG00000185009

1.24

PICALM

phosphatidylinositol binding clathrin assembly protein

ENSG00000073921

1.20

CLINT1

clathrin interactor 1

ENSG00000113282

2.11

NECAP1

NACAP endocytosis associated 1

ENSG00000089818

1.36

IGF2R

insulin-like growth factor 2 receptor

ENSG00000197081

2.19

M6PR

mannose-6-phosphate receptor (cation dependent)

ENSG00000003056

1.42

PIK3C2B

phosphoinositide-3-kinase, class 2, beta polypeptide

ENSG00000133056

1.79

EEA1

early endosome antigen 1

ENSG00000102189

1.91

LDLR

low density lipoprotein receptor

ENSG00000130164

2.01

LRP1

low-density lipoprotein receptor-related protein

ENSG00000123384

1.70

LDLRAP1

low density lipoprotein receptor adaptor protein

ENSG00000157978

1.29

ID

NAME

ADJ p VALUE

GO:0016197

endosome transport

1.06E-03

GO:0005905

coated pit

1.10E-03

GO:0030139

endocytic vesicle

1.10E-03

GO:0030131

clathrin adaptor complex

1.25E-03

GO:0030136

clathrin-coated vesicle

1.25E-03

GO:0030133

transport vesicle

1.69E-02

GO:0030135

coated vessicle

1.69E-02

GO:0030118

clathrin coat

2.09E-02

GO:0065002

intracellular protein transmembrane transport

2.12E-03

GO:0042325

regulation of phosphorylation

2.28E-03

GO:0006897

endocytosis

2.38E-02

GO:0030666

endocytic vesicle membrane

3.10E-03

GO:0045121

membrane raft

3.39E-02

GO:0005768

endosome

3.52E-03

GO:0032799

low-density lipoprotein receptor metabolic process

3.62E-03

GO:0001726

ruffle

5.84E-01

GO:0030117

membrane coat

5.84E-01

  1. (A) Fold-changes in endocytosis annotated genes. Fold changes were calculated after correcting the number of RNA-seq reads mapped to the gene in each condition by the total number of reads from the sequencing experiment for that condition. (B) Enrichment analysis of GO functional categories related to endocytosis. Adjusted p-values were obtained after Benjamini and Hochberg correction (Benjamini &[Hochberg 1995]). Significant categories (adjusted p-value <0.05) are indicated in bold.
Back to article page