Table 2 Level of BCL2 protein expression according to lymph node status, tumour grade, morphology, ER, PR, HER2 and CK5/6 status
Low BCL2 n (%) | High BCL2 n (%) | p valuea | ||
|---|---|---|---|---|
Node status | No nodal Involvement | 20 (64.5) | 140 (70.0) | |
Nodal Involvement | 11 (35.5) | 60 (30.0) | 0.54 | |
Grade | 1 | 3 (8.8) | 51 (24.9) | |
2 | 7 (20.6) | 114 (55.6) | ||
3 | 24 (70.6) | 40 (19.5) | 4x10-9 | |
Morphology | Ductal | 28 (80.0) | 159 (75.7) | |
Lobular | 2 (5.7) | 22 (10.5) | ||
Other | 5 (14.3) | 29 (13.8) | 0.68 | |
ER status | Negative | 27 (79.4) | 31 (15.3) | |
Positive | 7 (20.6) | 171 (84.7) | 1x10-14 | |
PR status | Negative | 20 (62.5) | 53 (26.6) | |
Positive | 12 (37.5) | 146 (73.4) | 5x10-5 | |
HER2 status | Negative | 29 (82.9) | 193 (92.3) | |
Positive | 6 (17.1) | 16 (7.7) | 0.07 | |
CK5/6 status | Negative | 23 (67.6) | 180 (90.5) | |
Positive | 11 (32.4) | 19 (9.5) | 0.0002 |