A BCL2 promoter polymorphism rs2279115 is not associated with BCL2 protein expression or patient survival in breast cancer patients

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Table 1 Breast cancer risk factors in case and control subjects

Variable		Controls	Cases	p values
Age	N	981	980
	Median (IQR)	57 (53–61)	59 (51–68)	p = 0.0004^a
Age at menarche	N	972	962
	Median (IQR)	13 (12–14)	13 (12–14)	p = 0.83^a
Age at menopause	N	537	517
	Median (IQR)	50 (47–52)	50(46–52)	p = 0.62^a
Age at first pregnancy	N	878	807
	Median (IQR)	23 (20–26)	24 (21–27)	p = 0.000001^a
Parity	N	981	980
	Median (IQR)	2 (2–3)	2(1–3)	p = 0.01^a
Menopausal status	N	981	978
	post	679 (69.2%)	653 (66.8%)
	pre	302 (30.8%)	325 (33.2%)	p = 0.25^b
Family history of breast cancer	N	981	980
	Yes	101 (10.3%)	142 (14.5%)
	No	880 (89.7%)	838 (85.5%)	p = 0.005^b

^a Mann Whitney U test. ^b Pearson χ² test. IQR: Inter-quartile range.
Positive family history was defined as the presence of at least one first degree relative with breast cancer.