Skip to main content
SpringerPlus

Table 3 Distribution of FRA expression relative to hormone receptor status and tumor grade in a Her2(−) metastatic breast cancer cohort a

From: Folate receptor alpha (FRA) expression in breast cancer: identification of a new molecular subtype and association with triple negative disease

Variable

FRA positive

FRA negative

Total

P valueb

 

N (%)

N (%)

  

Marker

    

  ER/PR(+)

3 (14%)

20 (86%)

23

 

  ER/PR/Her2(−)

19 (50%)

19 (50%)

38

0.0054

    

[ER/PR(+) vs ER/PR/Her2(-)]

Tumor Grade

    

  Grade 1

3 (30%)

7 (70%)

10

 

  Grade 2

11 (28%)

28 (72%)

39

1.0

    

(Grade 1 vs Grade 2)

  Grade 3

8 (67%)

4 (33%)

12

0.037

    

(Grade 1 or 2 vs Grade 3)

  Total Samples

22 (36%)

39 (64%)

61

 
  1. FRA folate receptor alpha, Her2 human epidermal growth factor receptor type 2, ER estrogen receptor, PR progesterone receptor.
  2. a All samples were whole tissue FFPE (formalin-fixed, paraffin-embedded) slides.
  3. b P values calculated via 2X2 contingency table analysis using Fisher’s exact test.
Back to article page