BRCA1 And BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin

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Table 1 Inclusion criteria for the probands

Group (n)	Criteria	Number of probands
EO (37)	Onset of cancer ≤40 years	37
Ashk-FH (40)	Onset of cancer ≤40 years with family history	12
	Onset of cancer >40 years with family history	28
FH (57)	Onset of cancer ≤40 years with family history	31
	Onset of cancer >40 years with family history	26
Total		134

n: total number of probands per group. EO: Early onset; Ashk: Ashkenazi; FH: Family history, defined as: at least 2 members of 1^st or 2^nd degree with breast and/or ovarian cancer.