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Table 3 Effect of PTL on growth of sarcoma 180 in mice

From: Purification and characterization of a novel plant lectin from Pinellia ternata with antineoplastic activity

 

Dose ※ (mg/kg)

Tumor weight (g)

Inhibitory rate *(%)

CTX

20.00

0.463 ± 0.180

68.3 ± 12.2

PTL

3.25

0.935 ± 0.160

36.2 ± 10.9

 

2.30

0.995 ± 0.131

32.1 ± 8.9

 

0.85

1.236 ± 0.132

15.6 ± 9.0

Negative control (0.9%NaCl)

-

1.465 ± 0.122

-

  1. The anti-tumoral effect was determined by examining the tumor weight and calculating the inhibition rate as described below. The value of P (p<0.005) was calculated according to the tumor weight at every experiment group.
  2. ※Each dose was tested in 12 mice every other day for 10 days;
  3. *Inhibitory rate = [(tumor weight of control mice-tumor weight of experimental mice)/tumor weight of control mice]x100%.
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