Table 3 Univariate analysis on covariates associated with HRQoL scores among children with Beta-Thalassemia Major
Physical QoL Score | p value | Correlation (r, p) | Psychosocial QoL score | p value | Correlation (r, p) | Total QoL score | p value | Correlation (r, p) | |
|---|---|---|---|---|---|---|---|---|---|
Age | |||||||||
2–4 years (n = 68) | 88.9 ± 21.6 | 0.001 | (−0.243, 0.000) | 86.1 ± 12.6 | 0.000 | (−0.229, 0.000) | 87.4 ± 14.2 | 0.000 | (−0286, 0.000) |
5–7 years (n = 43) | 83.2 ± 16.4 | 85.5 ± 10.7 | 84.5 ± 10.7 | ||||||
8–12 years (n = 61) | 75.7 ± 23.5 | 77.7 ± 14.3 | 76.7 ± 15.6 | ||||||
13–18 years (n = 69) | 77.5 ± 19.4 | 81.5 ± 12.4 | 79.9 ± 13.6 | ||||||
Comorbidity | |||||||||
Yes (n = 17) | 67.0 ± 25.9 | 0.008 | (−0.173, 0.007) | 76.9 ± 16.6 | 0.157 | (−0.093, 0.150) | 72.8 ± 18.5 | 0.026 | (−0.145, 0.024) |
No (n = 234) | 82.4 ± 20.5 | 82.9 ± 12.7 | 82.7 ± 13.9 | ||||||
Type of Iron chelation therapy | |||||||||
Only oral (n = 213) | 81.2 ± 21.3 | 0.103 | 82.0 ± 12.4 | 0.000 | 81.7 ± 13.9 | 0.003 | |||
Only subcutaneous (n = 3) | 67.7 ± 17.8 | 78.3 ± 19.2 | 74.6 ± 17.2 | ||||||
Oral +subcutaneous (n = 4) | 73.4 ± 14.6 | 75.4 ± 12.5 | 74.6 ± 13.0 | ||||||
No ICT (n = 21) | 86.1 ± 21.9 | 89.7 ± 17.2 | 88.1 ± 18.6 | ||||||
Frequency of Hospital visits/month | |||||||||
1 (n = 196) | 83.1 ± 20.4 | 0.012 | (−0.162, 0.009) | 82.9 ± 12.9 | 0.213 | (−0.50,0.420) | 82.9 ± 14.1 | 0.044 | (−0.127, 0.050) |
2 (n = 43) | 74.6 ± 23.2 | 81.3 ± 13.5 | 78.7 ± 15.4 | ||||||
3 (n = 2) | 51.6 ± 6.6 | 69.2 ± 1.2 | 63.0 ± 3.07 | ||||||