Non-invasive evaluation of pulmonary arterial blood flow and wall shear stress in pulmonary arterial hypertension with 3D phase contrast magnetic resonance imaging

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Table 2 Pulmonary artery dimensions and blood flow parameters in patients with PAH and healthy volunteers

	Healthy volunteers	PAH patients	p value
Diameter (mm)
MPA	13.0 ± 1.0	15.6 ± 2.5	0.038
RPA	8.0 ± 0.7	11.7 ± 1.7	0.001
LPA	9.1 ± 0.8	13.8 ± 7.6	0.097
Area (mm²)
MPA	537.6 ± 94.2	780.0 ± 272.2	0.058
RPA	233.7 ± 36.3	435.8 ± 132.2	0.003
LPA	262.3 ± 47.0	753.3 ± 897.8	0.209
Maximum blood flow velocity (m/sec)
MPA	0.41 ± 0.10	0.28 ± 0.09	0.019
RPA	0.41 ± 0.15	0.22 ± 0.07	0.006
LPA	0.32 ± 0.10	0.18 ± 0.07	0.010
Mean blood flow velocity (m/sec)
MPA	0.10 ± 0.02	0.07 ± 0.02	0.011
RPA	0.11 ± 0.04	0.06 ± 0.02	0.007
LPA	0.09 ± 0.02	0.06 ± 0.05	0.249
Maximum blood flow volume (L/min)
MPA	13.54 ± 2.83	12.74 ± 3.49	0.650
RPA	5.87 ± 1.08	5.96 ± 1.05	0.874
LPA	5.10 ± 1.50	4.85 ± 2.83	0.911
Mean blood flow volume (L/min)
MPA	3.14 ± 0.77	2.78 ± 0.34	0.240
RPA	1.53 ± 0.29	1.65 ± 0.55	0.618
LPA	1.38 ± 0.38	1.41 ± 0.62	0.909
Stroke volume (mL)
MPA	62.5 ± 15.6	54.9 ± 7.3	0.219
RPA	30.5 ± 5.8	32.7 ± 10.6	0.667
LPA	27.4 ± 7.5	27.7 ± 12.0	0.945

Data are expressed as mean ± standard deviation
PAH pulmonary arterial hypertension, MPA main pulmonary artery, RPA right pulmonary artery, LPA left pulmonary artery