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Table 2 multivariate analysis of TNBC prognostic factors by Cox regression model

From: Impact of central obesity on prognostic outcome of triple negative breast cancer in Chinese women

 

DFS

OS

P

HR

95.0 % CI

P

HR

95.0 % CI

Model 1: BMI ≥ 25 kg/m2 as a covariate into Cox regression model

 LVI: positive versus negative

0.012

2.165

1.182–3.965

0.045

2.075

1.017–4.237

 pT stage

0.045

  

0.033

  

 pT2 versus pT1

0.037

2.228

1.049–4.736

0.055

2.476

0.981–6.247

 pT3 versus pT1

0.020

3.417

1.217–9.593

0.010

4.672

1.453–15.021

 pN stage

0.018

  

0.048

  

 pN1 versus pN0

0.004

2.862

1.410–5.809

0.050

2.304

0.999–5.318

 pN2 versus pN0

0.008

3.016

1.331–6.831

0.009

3.460

1.370–8.736

 pN3 versus pN0

0.108

2.642

0.808–8.636

0.051

3.797

0.993–14.525

 BMI: BMI ≥ 25 kg/m2 versus BMI < 25 kg/m2

0.125

1.554

0.885–2.728

0.059

1.904

0.976–3.713

Model 2: WC ≥ 80 cm as a covariate into Cox regression model

 LVI: positive versus negative

0.011

2.202

1.199–4.043

0.029

2.226

1.083–4.574

 pT stage

0.041

  

0.031

  

 pT2 versus pT1

0.030

2.284

1.081–4.826

0.045

2.552

1.020–6.386

 pT3 versus pT1

0.019

3.395

1.218–9.466

0.009

4.635

1.457–14.745

 pN stage

0.013

  

0.033

  

 pN1 versus pN0

0.003

2.887

1.419–5.873

0.052

2.303

0.992–5.343

 pN2 versus pN0

0.005

3.231

1.433–7.289

0.005

3.770

1.499–9.477

 pN3 versus pN0

0.107

2.640

0.811–8.589

0.051

3.759

0.994–14.221

 WC: WC ≥ 80 cm versus WC < 80 cm

0.046

1.759

1.009–3.065

0.014

2.297

1.184–4.456

Model 3: WC ≥ 80 cm + BMI ≥ 25 kg/m2 as a covariate into Cox regression model

 LVI: positive versus negative

0.011

2.207

1.203–4.051

0.037

2.119

1.045–4.294

 pT stage

0.041

  

0.033

  

 pT2:pT1

0.031

2.280

1.080–4.814

0.050

2.496

1.001–6.225

 pT3:pT1

0.019

3.394

1.221–9.439

0.010

4.565

1.439–14.488

 pN stage

0.017

  

0.027

  

 pN1:pN0

0.004

2.816

1.384–5.730

0.049

2.306

1.002–5.307

 pN2:pN0

0.005

3.159

1.403–7.115

0.004

3.810

1.532–9.476

 pN3:pN0

0.115

2.576

0.793–8.366

0.045

3.850

1.029–14.413

 WC + BMI: WC ≥ 80 cm and BMI ≥ 25 kg/m2 versus WC < 80 cm or BMI < 25 kg/m2

0.031

1.845

1.059–3.212

0.010

2.377

1.230–4.593

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