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Table 2 Cognitive performance (raw test scores) at each time point for CT and NCT groups: mean (SD)

From: A feasibility study exploring the role of pre-operative assessment when examining the mechanism of ‘chemo-brain’ in breast cancer patients

 

Chemotherapy (n = 8)

No chemotherapy (n = 6)

T1

T2

T3

T1

T2

T3

RAVLT

 Supraspan (0–15)

7.3 (2.3)

7.3 (2.7)

7.2 (2.2)

10.3 (3.3)

9.0 (3.0)

9.4 (3.0)

 Total score (0–75)

56.0 (9.1)

52.4 (12.3)

54.2 (9.8)

62.7 (7.9)

61.3 (9.8)

61.8 (8.6)

 Delayed score (0–15)

12.5 (2.8)

11.3 (2.4)

11.3 (2.4)

11.5 (1.5)

12.7 (2.4)

12.3 (2.0)

Double letter cancellation

 Time (s)

185.0 (32.1)

174.3 (20.1)

179.4 (69.5)

176.7 (26.8)

163.7 (30.3)

160.0 (30.4)

 Total score

69.4 (3.3)

70.9 (2.1)

69.5 (2.9)

72.0 (3.3)

72.8 (2.6)

72.3 (3.2)

Letter number sequencing

 Total score

10.3 (3.2)

10.6 (3.7)

10.8 (3.3)

12.8 (3.0)

12.8 (2.6)

13.2 (3.0)

COWAT

 Total score

56.4 (15.5)

54.0 (16.6)

54.4 (15.0)

55.2 (9.9)

54.0 (6.5)

55.2 (9.0)

Stroop Colour Word Test

 Word card

101.1 (15.4)

101.0 (18.0)

97.8 (20.0)

113.2 (14.3)

114.7 (16.5)

113.8 (17.3)

 Colour card

78.0 (11.7)

77.0 (15.1)

77.0 (11.3)

87.3 (12.8)

86.0 (9.1)

87.3 (14.7)

 Colour-word card

45.3 (6.6)

47.1 (7.6)

47.5 (6.9)

52.0 (14.8)

55.8 (9.7)

56.3 (9.9)

 Interference score

1.5 (4.8)

3.8 (7.2)

4.7 (8.1)

2.9 (12.0)

6.9 (8.6)

7.1 (8.1)

Grooved Pegboard

 Dominant hand: time (s)

67.1 (7.2)

65.7 (9.3)

66.2 (7.5)

63.3 (6.6)

59.0 (5.7)

61.2 (6.8)

 Dominant hand: total

92.4 (7.4)

90.9 (9.3)

91.4 (7.7)

88.3 (6.6)

84.2 (5.7)

86.3 (6.8)

 Non-dominant hand: time (s)

76.4 (8.7)

75.4 (7.6)

75.4 (7.4)

78.0 (10.5)

66.8 (4.2)

70.4 (9.5)

 Non-dominant hand: total

101.4 (8.7)

100.4 (7.6)

100.5 (7.5)

103.5 (9.8)

91.8 (4.2)

95.6 (9.4)

FACT-B (0–112)

105.6 (7.8)

101.8 (17.5)

101.6 (12.9)

115.4 (10.8)

112.3 (13.3)

116.0 (18.0)

FACT-F (0–160)

114.6 (15.0)

111.8 (18.8)

107.5 (19.7)

128.9 (12.0)

125.6 (14.8)

127.2 (20.3)

FACT-Cog

 PCI (0–72)

49.9 (14.4)

42.9 (15.8)

36.8 (14.0)

49.8 (8.4)

47.2 (15.7)

48.0 (11.9)

 PCA (0–28)

18.6 (4.3)

13.3 (4.8)

13.3 (5.6)

16.8 (6.2)

18.2 (5.7)

18.0 (6.4)

 Oth (0–16)

14.3 (2.9)

13.9 (2.9)

14.9 (1.9)

14.8 (2.4)

14.8 (1.5)

15.2 (1.2)

 CogQOL (0–16)

12.9 (3.8)

11.1 (2.9)

11.3 (3.8)

9.5 (5.4)

12.7 (1.8)

12.5 (4.0)

TSQ (0–10)

4.4 (2.5)

3.9 (2.2)

3.3 (1.3)

4.8 (2.5)

3.0 (2.8)

2.2 (1.9)

  1. RAVLT Rey Auditory Verbal Learning Test, COWAT Controlled Word Association Test, FACT-B Functional Assessment of Cancer Therapy-Breast, FACT-F Functional Assessment of Cancer Therapy-Fatigue, FACT-Cog Functional Assessment of Cancer Therapy-Cognitive function, PCA perceived cognitive abilities, PCI perceived cognitive impairment, Oth deficits observed or commented on by others, CogQOL impact on quality of life, SD standard deviation, TSQ Trauma Screenings Questionnaire