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Table 2 Genotype frequencies of single nucleotide polymorphisms in HSP90AA1 gene

From: Single nucleotide polymorphisms of HSP90AA1 gene influence response of SLE patients to glucocorticoids treatment

Polymorphisms (Minor allele)

Sensitive (n = 128)

Insensitive (n = 105)

Overall (n = 233)

HWE P value

Wild type

Heterozygous

Homozygous mutants

Wild type

Heterozygous

Homozygous mutants

Wild type

Heterozygous

Homozygous mutants

rs2298878 (A)

121 (94.53)

7 (5.47)

0 (0)

97 (92.38)

8 (7.62)

0 (0)

218 (93.56)

15 (6.44)

0 (0)

0.612

rs7157967 (C)

123 (96.09)

5 (3.91)

0 (0)

103 (98.10)

2 (1.90)

0 (0)

226 (97.00)

7 (3.00)

0 (0)

0.816

rs7160651 (A)

72 (56.25)

50 (39.06)

6 (4.69)

75 (71.43)

26 (24.76)

4 (3.81)

147 (63.09)

76 (32.62)

10 (4.29)

0.964

rs10873531 (G)

61 (47.66)

59 (46.09)

8 (6.25)

67 (63.81)

31 (29.52)

7 (6.67)

128 (54.94)

90 (38.63)

15 (6.43)

0.877

rs1190597 (G)

107 (83.59)

19 (14.85)

2 (1.56)

94 (89.53)

10 (9.52)

1 (0.95)

201 (86.26)

29 (12.45)

3 (1.29)

0.112

rs11547523 (G)

111 (86.72)

16 (12.50)

1 (0.78)

94 (89.52)

11 (10.48)

0 (0)

205 (87.98)

27 (11.59)

1 (0.43)

0.913

rs2298877 (T)

68 (53.13)

53 (41.41)

7 (5.46)

71 (67.62)

27 (25.71)

7 (6.67)

139 (59.66)

80 (34.33)

14 (6.01)

0.585