Inhibitory effects of tibial nerve stimulation on bladder neurophysiology in rats

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Table 1 Statistical comparison of estimated parameters in pre- and post-stimulation measurements

	Prestimulation saline (I)	Prestimulation AA (II)	Poststimulation AA (III)
Automatically calculated
Threshold afferent activity (µV)	0.21 ± 0.02	0.23 ± 0.04^ф	0.19 ± 0.01*
Maximum afferent activity (µV)	0.25 ± 0.04	0.41 ± 0.07^ф	0.22 ± 0.04*
Threshold pressure, p_thres (cmH₂O)	5.2 ± 2.4	4.4 ± 2.7^N.S.	5.4 ± 2.8^N.S.
Maximum pressure, p_max (cmH₂O)	34.4 ± 7.0	32.5 ± 7.8^N.S.	30.5 ± 5.2^N.S.
Pressure rise time (s)	59.2 ± 55.9	54.6 ± 55.1^N.S.	54.6 ± 47.9^N.S.
Slope (µV/cmH₂O)	1.6 ± 1.4	1.9 ± 1.5^ф	0.7 ± 0.6*
Offset (µV)	0.21 ± 0.03	0.22 ± 0.04^N.S.	0.19 ± 0.02^N.S.
Volume, V_thres (mL)	0.84 ± 0.2	0.53 ± 0.2^ф	0.76 ± 0.3*
Compliance (mL/cmH₂O)	0.17 ± 0.03	0.10 ± 0.07^ф	0.17 ± 0.06*
Manually calculated
Threshold afferent activity (µV)	0.21 ± 0.02	0.23 ± 0.04^ф	0.20 ± 0.21*
Threshold pressure (cmH₂O)	6.5 ± 2.9	5.3 ± 2.3^N.S.	6.7 ± 2.5^N.S.
Rise time (s)	53.2 ± 55.9	48.6 ± 55.1^N.S.	45.5 ± 33.9^N.S.

Mean ± SD of the estimated parameters in control saline, prestimulation and poststimulation AA measurements, n = 72 measurements (saline = 18, prestimulation AA = 27, and poststimulation AA = 27). The symbols ф and * represent the statistical significance (p < 0.05) between group I vs II and II vs III respectively. N.S. indicates no statistical difference (p > 0.05) between the groups