Intestinal tuberculosis | Crohn’s disease | |
---|---|---|
Clinical presentations | ||
Age | Any age | 20–50 |
Obstructive symptoms | ++ | + |
Stricture pattern | Short, single | Long, multiple (skip lesions) |
Mucosal ulceration | Circumferential | Longitudinal |
Fistula | Few | 35–50% |
Perianal disease | Few | >1/3 |
Ascites | + | Rare |
Histological features | ||
Caseous necrosis | 22–40% | 0% |
Granulomatous inflammation | 78–100% | 28–61% |
Confluent granuloma | 42–60% | 0–3% |
≧5 granulomas/biopsy | 40–45% | 0–24% |
Large granulomasa | 51–90% | 0–5% |
Submucosal granulomas | 39–45% | 5–12% |
Ulcers lined by bands of epithelioid histiocytes | 45–61% | 0–8% |
Disproportionate submucosal inflammation | 65–67% | 5–10% |