Figure 4From: The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastomaIncreased TRAIL sensitivity by DMC is caspase-dependent. (A) Cell viability was assessed after 24h co-treatment with rhTRAIL WT (0–250 ng/ml) and 0, 25 or 50 μM DMC using a MTS assay. (B) Western blot analysis of A172 (5h) and U87 (24h) cells treated with either rhTRAIL WT (0, 10 or 100 ng/ml) and/or DMC (0, 25 or 50 μM) for caspase-8, -9, -3 and PARP. β-actin served as a loading control.Back to article page