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Figure 1

From: Selective head cooling for the treatment of neurologic complications of acute liver failure in a newborn with disseminated herpes infection

Figure 1

Laboratory, TCD and EEG data. A. Selected laboratory results showing changes in liver enzymes and synthetic function beginning with admission of day of life (DOL) 5. B, Continuous EEG on DOL7 showing focal bifrontal and bitemporal epileptiform discharges. C. Serial transcranial doppler results showing undetectable end-diastolic (ED) velocities in the middle cerebral artery on DOL 11 during hypothermia and DOL 14 after rewarming, with recovery of flow during head cooling on DOL 12 and early after re-warming on DOL 14. Time-averaged mean of the maximal velocities (Tamx) show initial reduction in velocity during cooling, followed by recovery. D, Continuous EEG on DOL13 showing right sided electrographic seizure. ALT, alanine aminotransferase; AST, aspartate aminotransferase; TCD, transcranial doppler.

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