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Table 4 Proportional cox regression models, n = 161,228

From: Marital status and its effect on lung cancer survival

  

Model 1

Model 2

Model 3

Model 4

Model 5

Prognostic factors

Category

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Marital status

Never married

1.00

 

1.00

 

1.00

 

1.00

 

1.00

 
 

Separated/ Divorced

1.03 (1.01, 1.05)

0.003

1.03 (0.89, 1.20)

0.654

1.03 (0.96, 1.10)

0.461

1.04 (1.01, 1.07)

0.008

1.05 (1.02, 1.08)

<.001

 

Widowed

0.81 (0.80, 0.83)

<.001

0.82 (0.59, 1.14)

0.240

0.77 (0.63, 0.94)

0.010

0.87 (0.82, 0.91)

<.001

0.88 (0.84, 0.93)

<.001

 

Married

0.70 (0.69, 0.71)

<.001

0.71 (0.53, 0.95)

0.021

0.70 (0.60, 0.83)

<.001

0.82 (0.78, 0.87)

<.001

0.85 (0.81, 0.89)

<.001

Race

White

1.00

 

1.00

 

1.00

 

1.00

 

1.00

 
 

Black

1.12 (1.10, 1.14)

<.001

0.97 (0.88, 1.05)

0.438

1.04 (1.01, 1.07)

0.021

0.99 (0.95, 1.02)

0.472

0.99 (0.95, 1.02)

0.391

 

Other

0.91 (0.85, 0.97)

0.005

0.91 (0.85, 0.97)

0.007

1.00 (0.93, 1.08)

0.944

0.96 (0.89, 1.04)

0.314

0.85 (0.78, 0.93)

<.001

Hispanic origin

Non-Hispanic

1.00

 

1.00

 

1.00

 

1.00

 

1.00

 
 

Hispanic

0.98 (0.96, 1.01)

0.148

0.93 (0.85, 1.02)

0.130

0.97 (0.90, 1.06)

0.499

0.94 (0.89, 0.99)

0.026

0.91 (0.86, 0.96)

<.001

SES

Lowest

1.00

 

1.00

 

1.00

 

1.00

 

1.00

 
 

Middle-Low

0.90 (0.89, 0.92)

<.001

0.93 (0.90, 0.97)

<.001

0.95 (0.92, 0.98)

<.001

0.96 (0.93, 0.98)

0.002

0.96 (0.94, 0.99)

0.005

 

Middle-High

0.84 (0.83, 0.85)

<.001

0.88 (0.84, 0.93)

<.001

0.90 (0.86, 0.93)

<.001

0.92 (0.89, 0.95)

<.001

0.92 (0.90, 0.95)

<.001

 

Highest

0.77 (0.76, 0.79)

<.001

0.82 (0.77, 0.88)

<.001

0.85 (0.80, 0.91)

<.001

0.88 (0.85, 0.92)

<.001

0.89 (0.85, 0.92)

<.001

  1. Model 1: Univariate.
  2. Model 2: Multivariate only with Marital status + Race/Ethnicity/SES.
  3. Model 3: Multivariate - Marital status + Race/Ethnicity/SES + demographics.
  4. Model 4: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical.
  5. Model 5: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical + individual comorbidities.
  6. Notes: there is no interaction between marital status and race, ethnicity and SES respectively.
  7. SES = Socioeconomic Status (percent living below poverty line); Lowest (≥20%); Middle-low (≥10% and <20%); Middle-high (≥5% and <10%); Highest (<5%).
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